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Table 2 Descriptive statistics of numeric variables (All variables have a total count of 407, FH indicates the fractional helical content)

From: Prediction of the synergistic effect of antimicrobial peptides and antimicrobial agents via supervised machine learning

Category

Variables

Unit

Unique

Mean

SD

Min

Max

AMP Characteristics

Length

a.a.

20

14.39

5.8

6

37

Molecular Weight

g/mol

65

1847.29

610.31

1044.23

4003.84

Normalized Hydrophobicity

\(\Delta\)G

59

0.6

1.1

-1.86

3.23

Net Charge

N/A

11

5.86

2.12

1

11

Isoelectric Point

pH(I)

18

13.63

0.96

9.93

14

Penetration Depth

Ã…

13

16.26

5.04

10

30

Tilt Angle

°

46

85.89

28.86

13

169

Disordered Conformation Propensity

FH

58

-0.31

0.45

-1.46

0.82

Linear Moment

kgxm/s

34

0.32

0.15

0

0.57

Amphiphilicity Index

N/A

60

2.14

1.24

0

5.3

Average Hydrophilicity

\(\Delta\)G

48

0.03

0.45

-0.98

2.16

Ratio of Hydrophilic Residues/Total

N/A

32

40.13

11.46

10

90

MIC of AMP

\(\mu\)g/mL

92

34.34

58.17

0.25

512

Antimicrobial Agent Characteristics

Physiological Charge

N/A

8

1.3

2.14

-2

5

LogP

N/A

36

-1.21

3.38

-8.6

4.1

Water Solubility

mg/mL

36

5.79

15.54

0.01

92.3

pKa

mol/L

35

7.48

4.04

2.42

12.68

Molecular Weight

g/mol

37

677.04

360.61

299.35

1449.3

MIC of Antimicrobial Agent

\(\mu\)g/mL

167

66.21

161.18

0.001

2048

Outcome

FIC Index

N/A

101

0.63

0.47

0.01

1.98